http://www.OJRD.com/content/1/1/37/comments The latest comments on the article 'Ollier disease' 2008-07-09T00:00:00Z This is an RSS newsfeed from BioMed Central It is intended to be used with an RSS reader. For more information about RSS newsfeeds from BioMed Central, visit http://www.biomedcentral.com/info/about/rss/ http://www.OJRD.com/content/1/1/37/comments#304565 <p>I am a 34 year old woman with Ollier's disease. I have had this disease for longer than I can remember. I have <b>never</b> met anyone else with it either. This is the first article that I've read that explains it in terms that I can understand. This is also the first time I have read an article that speaks what I have been going through thoroughly. I have had about 20 operations on this disease;and I am told that I will always have to have more.</p> Karen Fredette 2008-07-09T00:00:00Z http://www.OJRD.com/content/1/1/37/comments#284539 <p>The Relation Between Chromosomal Abnormality and Enchondromatosis</p><p>Saliha Senel, M.D.Department of pediatrics, Dr Sami Ulus Children&#8217;s Hospital, Ankara, TURKEY</p><p>Nilufer Karadeniz, M.D. Department of Genetics, Zubeyde Han&#305;m Hospital, Ankara, TURKEY</p><p>Emrah Senel, M.D. Department of pediatric surgery, Diskapi Children&#8217;s Hospital, Ankara, TURKEY</p><p>Correponding author;</p><p>Saliha Senel M.D.</p><p>Dr Sami Ulus Children&#8217;s Hospital, Telsizler ,Ankara, Turkey</p><p>Phone: +90 312 3056014</p><p>Fax: +90 312 3170353</p><p>E mail: drsaliha007@yahoo.com.tr</p><p>The Relation Between Chromosomal Abnormality and Enchondromatosis</p><p>Dear Editor;</p><p>We read with great interest &#8216;Ollier disease&#8217; in the September 2006 issue of &#8216;Orphanet journal of rare diseases&#8217;in which authors stated that there were no tumor spesific chromosomes or chromosomal regions associated with enchondromas (1). </p><p>The relation between enchondromatosis and chromosomal abnormality is not fully known but we think the authors had to mention about the finding of Nakayama et al. that demonstrated an excess of heterochromatin in the q band of the chromosome 1 in a chordoma associated with Maffucci syndrome which is characterized by enchondromas associated with hemangiomas (2).</p><p>References:</p><p>1.Silve C, J&#252;ppner H. Ollier disease. Orphanet J Rare Dis. 2006;22;1:37.</p><p>2. Nakayama Y, Takeno Y, Tsugu H, Tomonaga M. Maffucci&#8217;s syndrome associated with intracranial chordoma : a case report. Neurosurgery. 1994;34:907-909.</p> Saliha Senel 2007-05-30T00:00:00Z