Table 1

Prevalence of major findings in the NIH cohort of patients with fibrous dysplasia/McCune-Albright syndrome

Clinical finding

% patients1


Fibrous dysplasia

98

Café-au-lait spots

66

Gonadal abnormalities

Male: (ultrasound)2

70

Female: precocious puberty

50

Thyroid abnormalities

Abnormal ultrasound (U/S)

66

Hyperthyroid + abnormal U/S

28

Renal phosphate wasting

43

Hypophosphatemia

10

Growth hormone excess

21

Cushing’s syndrome

4


1 n = 140; 58 males, 82 females

2 detected on ultrasound

Collins et al. Orphanet Journal of Rare Diseases 2012 7(Suppl 1):S4   doi:10.1186/1750-1172-7-S1-S4

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