Table 3 |
||||||||||||
|
Summary of studies concerning IVIG for TEN |
||||||||||||
|
Trent |
Viard |
Prins |
Campione |
Al-Mutairi |
Shortt |
Tan |
Stella |
Rajaratnam |
Bachot |
Brown |
Schneck |
|
|
2003 |
1998 |
2003 |
2003 |
2004 |
2004 |
2005 |
2007 |
2010 |
2003 |
2004 |
2008 |
|
|
(80) |
(44) |
(73) |
(76) |
(74) |
(78) |
(79) |
(82) |
(81) |
(72) |
(75) |
(69) |
|
|
|
||||||||||||
|
Study design |
Retro |
Prosp |
Retro |
Prosp |
Prosp |
Retro |
Retro |
Retro |
Retro |
Prosp |
Retro |
Retro |
|
N/ |
N/ |
N/ |
N/ |
N/ |
N/ |
N/ |
Cont |
N/ |
N/ |
N/ |
Cont |
|
|
Cont |
Cont |
Cont |
Cont |
Cont |
Cont |
Cont |
Cont |
Cont |
Cont |
|||
|
|
||||||||||||
|
Patients |
24 |
10 |
48 |
10 |
12 |
16 |
12 |
23 |
14 |
34 |
24 |
75 |
|
|
||||||||||||
|
Detachm.(%) |
44 |
39 |
45 |
49 |
58 |
"65" |
--- |
--- |
"44" |
19 |
49 |
--- |
|
|
||||||||||||
|
Total dose IVIG (g/kg) |
4 |
3 |
3 |
2 |
2-5 |
2.8 |
2 |
--- |
3.3 |
2 |
1.6 |
1.9 (0.7-2.3) |
|
|
||||||||||||
|
Predicted mortality (SCORTEN/APACHE*) in % |
33 |
--- |
--- |
35 |
--- |
38 * |
--- |
35.8 |
36 |
24 |
28.6 |
25 |
|
|
||||||||||||
|
Actual mortality in % |
4 |
0 |
12 |
10 |
0 |
25 |
8 |
26 |
21 |
32 |
41.7 |
34 |
|
|
||||||||||||
|
Harr and French Orphanet Journal of Rare Diseases 2010 5:39 doi:10.1186/1750-1172-5-39 |
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