Table 2 |
||
|
Prevalence of individual symptoms of hypothyroidism at the time of diagnosis. (modified from: Alm et al. Brit Med J 289:1171-175, 1984 [13].) |
||
|
Features listed in questionnaire |
Group 1 (n = 215) Initial T4 ≤ 30 nmol/L % with feature |
Group 2 (n = 232) Initial T4 > 30 nmol/L % with feature |
|
|
||
|
Prolonged Jaundice |
59 |
33** |
|
Feeding Difficulty |
35 |
16** |
|
Lethargy |
34 |
14** |
|
Umbilical Hernia |
32 |
18* |
|
Macroglossia |
25 |
12* |
|
Constipation |
18 |
10 |
|
Cold or mottled skin |
18 |
10 |
|
Hypothermia |
3 |
3 |
|
No symptoms |
16 |
33** |
|
Other clinical features reported: |
||
|
Abnormal cry |
7 |
6 |
|
Edema |
5 |
3 |
|
Hypothyroid appearance |
6 |
2 |
|
Hypotonia |
3 |
3 |
|
|
||
|
**p < 0.001, *p < 0.01. |
||
|
Rastogi and LaFranchi Orphanet Journal of Rare Diseases 2010 5:17 doi:10.1186/1750-1172-5-17 |
||
