Table 1

Frequency of the main clinical characteristics of inv dup(15) or idic(15) syndrome

Exceeding 75%

From 25% to 50%

Below 25%

Hypotonia, lax ligaments

Brain abnormalities

Congenital heart defects

Developmental delay/Intellectual disability

Genitourinary tract defects


Autistic behavior

Growth retardation


Minor dysmorphic features (mainly involving the face)

Battaglia Orphanet Journal of Rare Diseases 2008 3:30   doi:10.1186/1750-1172-3-30

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