| Bleomycin μg/ml |
0 |
0.1 |
0.25 |
0.5 |
|
|
||||
| negative control |
0.06 |
0.48 |
0.5 |
0.98 |
| patient |
0.02 |
1.04 |
1.28 |
1.78 |
| positive control |
0.06 |
1.33 |
1.52 |
2.4 |
|
Chromosome breakage rates (percent breaks per cell) of peripheral blood mononuclear cells exposed to the respective concentrations of the radiomimetic bleomycin for four hours. Negative control = blood samples from healthy donors; positive control = blood sample from a proven AT patient. | ||||
Gruhn et al. Orphanet Journal of Rare Diseases 2007 2:5 doi:10.1186/1750-1172-2-5 |
||||