|
Extent of organ involvement |
|||
| Stage |
Skin |
Liver (bilirubin) |
Gut (stool output/day) |
|
|
|||
| 0 |
No GVHD rash |
< 2 mg/dl |
< 500 ml/day or persistent nausea. |
| 1 |
Maculopapular rash< 25% BSA |
2–3 mg/dl |
500–999 ml/day |
| 2 |
Maculopapular rash 25 – 50% BSA |
3.1–6 mg/dl |
1000–1500 ml/day |
| 3 |
Maculopapular rash > 50% BSA |
6.1–15 mg/dl |
Adult: >1500 ml/day |
| 4 |
Generalized erythroderma plus bullous formation |
>15 mg/dl |
Severe abdominal pain with or without ileus |
| Grade |
|||
| I |
Stage 1–2 |
None |
None |
| II |
Stage 3 or |
Stage 1 or |
Stage 1 |
| III |
- |
Stage 2–3 or |
Stage 2–4 |
| IV |
Stage 4 or |
Stage 4 |
- |
Jacobsohn and Vogelsang Orphanet Journal of Rare Diseases 2007 2:35 doi:10.1186/1750-1172-2-35 |
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