Table 2

Main antibodies associated with Paraneoplastic neurological syndromes

Antibodies

Main associated neurological syndromes

Cancer

Hu-Ab (ANNA1-Ab**)

Sensory neuronopathy

Encephalomyelitis

Chronic gastrointestinal pseudoobstruction

Cerebellar ataxia

Limbic encephalitis

SCLC

Yo-Ab (PCA1-Ab**)

Subacute cerebellar ataxia

Ovary, breast, uterus

CV2-Ab (CRMP5-Ab**)

Cerebellar ataxia

Sensory-motor neuropathy

Uveitis, retinopathy

Encephalomyelitis

SCLC, thymoma

Ri-Ab (ANNA2-Ab**)

Opsomyoclonus

Cerebellar ataxia

Breast, SCLC

Amphiphysin-Ab

Stiff-person syndrome

Sensory neuronopathy

Encephalomyelitis

Breast, SCLC

Tr-Ab

Cerebellar ataxia

Hodgkin's disease

Ma2-Ab (Ta-Ab**)

Limbic encephalitis

Testicular

CAR-Ab

Retinopathy

Breast, SCLC

**Alternative nomenclature which can be found in the literature

Honnorat and Antoine Orphanet Journal of Rare Diseases 2007 2:22   doi:10.1186/1750-1172-2-22