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Comparison of several features in PNDM and TNDM cases in the French cohort (n = 50) (adapted from [9]). |
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| PNDM n = 21 |
TNDM n = 29 |
P value |
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| Gestational age (weeks) |
39.2 ± 1.6 |
38.2 ± 2.2 |
P = 0.15 |
| Birth weight (g) |
2497 ± 690 |
1987 ± 510 |
P < 0.006 |
| Birth length (cm) |
47.5 ± 2.4 |
44.3 ± 3.4 |
P < 0.006 |
| Head circumference (cm) |
33 ± 1.9 |
31.5 ± 1.8 |
P < 0.02 |
| Intrauterine growth retardation |
n = 7/19 36% |
n = 20/27 74% |
P < 0.03 |
| Median age at diagnosis (days) (range)* |
27 (1–127) |
6 (1–81) |
P < 0.01 |
| Initial insulin dose (unit/kg/day) |
1.4 ± 1.2 |
0.6 ± 0.25 |
P < 0.006 |
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* Given the non-Gaussian distribution of age in the study population, the nonparametric Mann-Whitney U-test was used to compare age in the two groups. | |||
Polak and Cavé Orphanet Journal of Rare Diseases 2007 2:12 doi:10.1186/1750-1172-2-12 |
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