Table 4

Staging of retinoblastoma

Ocular fundus under general anesthesia +

Any patient with retinoblastoma Schema, photographs, ultrasonography Reese grouping, new grouping
Brain and orbit CT scan or MRI +

Almost any patient with retinoblastoma (except neonatal screened patients with tumor respecting the head of optic nerve)
CSF cytology Bone marrow cytohistology +

When enucleation is necessary and shows histopathologic risk factors
Brain and spinal axis MRI Bone scan

Only in case of orbital, lymph node and/or distant metastatic diseases

CT – computed tomography

MRI – magnetic resonance imaging

CSF – cerebrospinal fluid

Aerts et al. Orphanet Journal of Rare Diseases 2006 1:31   doi:10.1186/1750-1172-1-31

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